Hi Gloria,
I think you are beginning the process correctly and asking the right questions. The recipient institution has the right/responsibility to determine the disposition of the award going forward. The F&A issue is one appropriate consideration -- i.e., what effect will the possible scenarios have on the direct costs provided and what will be the impact to the research going forward -- as is the oversight and direction of the award at your institution -- with or without the award staying in the US. Either way, a new PI will likely be needed at your institution as either the PI of the prime award, or as PI of the sub from the UK.
At my institution, a lot of the weight in such a decision would likely be given to the original PI and his or her department. How will such decisions impact future careers (the PIs, the students, the lab, other researchers, etc)?
However you decide, each possibility will also likely require going back to NIH for revisions to the original research plans. So another consideration might be the time involved to process the NIH approvals for such a planned revision. Transferring an award may take a several months, other revisions may go quicker.
We usually give primary consideration to the impact on the research and the researchers.
I hope this is helpful.
-Norm
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Norman Hebert
Director International Research Administration
Brown University
Providence, RI
401-863-6791
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